Wood Buffalo National Park straddles the borders of the province of Alberta and Northwest Territories. I travelled to the park from Yellowknife, which is the unpolished but charming capital of Northwest Territories. My understanding is that while most of Wood Buffalo National Park lies in Alberta, the park and its trails are more accessible by car if you enter from the north, that is to say, from Northwest Territories.
On the long drive from Yellowknife to the park, I saw many bisons by - and on - the road. Although the bisons that I encountered were calm and unbothered by me, please keep your distance from these large beasts as they could seriously injure you if they feel harassed by you. Also, please be aware of bears in the park. I spent time admiring the bear tracks I found during a hike. Or at least I did, until I started to wonder about the freshness of the bear tracks.
Wood Buffalo National Park lacks the grandeur of Northwest Territories' other UNESCO world heritage site, i.e., Nahanni National Park. There are no majestic mountains or valleys in Wood Buffalo. However, everything is wild here, the rivers, the animals, and the experience. I wouldn't recommend visiting Canada, or even Northwest Territories, for Wood Buffalo, but it is definitely a worthwhile place to explore if you are in northern Alberta or southern Northwest Territories.