Although it was rainy during most of my visit, I found the city of Santa Ana de los RĂos de Cuenca to be the most charming of the cities I visited on the Ecuadorian mainland this past June. I arrived at night, but the room in the former monastery I stayed in had a magnificent view of the illuminated blue-hued domes of the New Cathedral. The next morning I ventured out in the rain to see both the New and Old Cathedrals and the Plaza Calderon, in the heart of the old city. The Old Cathedral is now a museum, and worth a visit, but I appreciated the architecture of the New Cathedral more. Later in the day, as the rain cleared, I embarked on a sightseeing tour via a double-decker bus departing from Plaza Calderon. I chose the southern tour route, which I highly recommend, as it includes the Mirador with its fine view of the city. The upper level of the tour bus offers an incredible view of the cobble-stoned streets and colonial architecture of the old town. Also not to be missed in Cuenca are the Panama hat factories, where you can watch some of Cuenca's more famous exports being made. I would have loved to have had more time in Cuenca.
Logistics: The downtown section of Cuenca is pedestrian-friendly. There is a local sightseeing bus with regular departures from Plaza Calderon, offering tours of the northern and southern parts of the city.