The highway runs through the city, including the historic center

Ecuador Highway 35 passes through Quito

Ecuador Highway 35 passes through Cuenca

Highway 190 from Mexico City passes through the city on its way to the Guatemalan frontier at Ciudad Cuauhatemoc where it becomes CA1

Tapantí-Macizo de la Muerte National Park - The border of this national park more or less follows the outline of the highway for some 20-30 km, between the towns of Trinidad and Villa Mills
See www.destinationcr.com

Highway 190 from Mexico City passes through the city on its way to the Guatemalan frontier at Ciudad Cuauhatemoc where it becomes CA1

Observation tower is along the highway

The Pan-American Highway (as Mexico Highway 85D) enters Mexico City.

The map of the Park on the UNESCO Web site shows "Carretera Panamericana Proyecto" passing across it in the south

The highway is interrupted here for about 100km

Churches of Castro, Nercon

A few 100 meters from the highway (Ruta 5)